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Food Intolerance by Maurice H. Lessof (auth.)

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By Maurice H. Lessof (auth.)

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Lehman (1980b) showed that the results of this test varied so greatly from one day to another that it was of no diagnostic value. Its unreliability has been confirmed in an assessment by the American Academy of Allergy and the National Centre for Health Care Technology (van Metre, 1987). , 1987). 5. Diagnosis in environmental control units. To exclude pollen and other airborne substances that might provoke symptoms, several clinical ecologists have established 'environmental control units' which require filtered air and are entered through double-doors.

In a further study which tested a different hypothesis, childhood behaviour disorders which had been attributed to 'sugar reactions' were not confirmed when a challenge dose of sugar was given blind (Rapoport, 1982-3). Some of the confusion which surrounds this issue stems from the fact that children who are diagnosed as hyperactive in some countries are most likely to be labelled as having a conduct disorder in others. 1% of this population are affected. Complaints of a child's hyperactive behaviour are common reasons for referral to a child psychiatrist, especially in boys, who are referred four times more frequently than girls.

The study then focused on the food additive problem. Individual claims were cross-checked by interviews, clinical assessment and, where appropriate, a series of daily challenge tests, in which capsules of either food additives or inert (placebo) substances were given over a 20-day period. As neither the patient nor the doctor was aware of the contents of the capsules taken, the trial was 'double-blind'. As both the test substances and inert placebos were taken in the capsules, the trial was 'placebo-controlled'.

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