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The space of closed subsets by A.H. Pavel

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By A.H. Pavel

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492(2–3), 159–167, 2004. 57. , Inducibility of c-Fos protein in visuo-motor system and limbic structures after acute and repeated administration of nicotine in the rat, Synapse, 29(4), 343–354, 1998. 58. D. , A comparison of sustained-release bupropion and placebo for smoking cessation [see comment], N. Engl. J. , 337(17), 1195–1202, 1997. 59. I. , Enantioselective effects of hydroxy metabolites of bupropion on behavior and on function of monoamine transporters and nicotinic receptors, Mol. , 66(3), 675–682, 2004.

N. , Bupropion in depression. II. The role of metabolites in clinical outcome, Arch. Gen. Psychiatry, 45(2), 145–149, 1988. 73. H. , Pharmacokinetics of bupropion and its metabolites in cigarette smokers versus nonsmokers, J. Clin. , 37(8), 737–743, 1997. 74. Fredrickson, P. , Blockade of nicotine-induced locomotor sensitization by a novel neurotensin analog in rats, Eur. J. , 458(1–2), 111–118, 2003. 75. Fredrickson, P. , 979(1–2), 245–248, 2003. 76. B. , alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells, Proc.

A recent investigation of this connection using retrograde tracing and electron microscopy showed that the LDTg makes asymmetric, presumably excitatory, contacts preferentially onto VTA dopamine neurons that project to the nucleus accumbens [30]. Symmetric, presumably inhibitory or cholinergic, contacts were also seen on both dopaminergic and nondopaminergic VTA neurons [30]. Presynaptic structures that express the vesicular acetylcholine transporter, a marker for cholinergic terminals, synapse onto VTA neurons that show little or no expression of the dopamine transporter which suggests significant cholinergic innervation of nondopamine neurons [32].

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